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PRODUCTS CNTER當(dāng)前位置:首頁(yè)產(chǎn)品中心Leading BiologyV系列AMM11941VCytochrome P450 2C9 (CYP2C9) Mouse Monoclonal Anti
CYP2C9 (Cytochrome P450 2C9) mouse monoclonal antibody, clone LBI1D7
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ARTICLESThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq]
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